Endocrine Abstracts

Neuroendocrine tumors (NETs) represent the second most common malignancy of the small bowel (SB) and despite their indolent nature, NET liver metastasis (NETLMs) will develop in 50 to 60% of patients. Although there have been recent advances in the therapeutic armamentarium in patients with advanced NETs, surgical resection remains the only potentially curative intervention for patients with NETLMs. However, patients whose liver has been significantly invaded by the tumour (mo...

Genetic predisposition to autoimmunity is probably predominant. Major histocompatibility complex (MHC) alleles and non-MHC loci such as polymorphism of the cytotoxic T lymphocyte antigen-4 (CTLA4) gene have been identified as susceptibility markers. The autoimmune thyroid diseases are the most common organ-specific autoimmune diseases. They are characterized by the infiltration of the parenchyma by immune cells including T and B cells as well as macrophages. Ones a T cell is a...

The strong link between bone mass and body composition is widely recognized but only few studies were selectively performed on healthy subjects with body mass index within normal limits. We aimed to evaluate the influence of body composition on bone mass in apparently healthy young non-obese men and women (n=40). To reveal the effect of menopausal transition on the fat mass content, fat mass distribution and fat mass-bone mineral density relationship we compared body co...